Topic

long-term

2 posts on this topic, sorted most recent first.

6 May 2026·5 min read·science
GLP-1 and bone density: what the long-term data actually shows
Rapid weight loss is associated with bone density changes. The GLP-1 trial data on bone is more nuanced than the headlines suggest. Here's what's known, what's contested, and what to do about it.
5 May 2026·5 min read·evidence
What the second year on tirzepatide actually looks like
Almost all the public conversation about tirzepatide is about the first six months. The trial data, the dramatic before-and-afters, the side-effects window. The second year is where the harder questions live: maintenance dose, plateau, lean mass, and the question nobody asks until they're in it.

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