·4 min read·compound-guide
What to do if you missed a tirzepatide dose
The window for catching a missed weekly dose is wider than most patient handouts say. Here's what actually matters and how to think about getting back on cycle.
Topic
dose
5 posts on this topic, sorted most recent first.
- ·5 min read·compound-guide
When tirzepatide isn't working: troubleshooting non-response
About 15-20% of patients respond poorly to tirzepatide. Most cases are workflow problems with fixable causes. Here's the diagnostic decision tree.
- ·4 min read·evidence
What 'maintenance dose' actually means and why nobody explains it
A clinic in Bangkok used the phrase 'maintenance dose' three times in one consultation without ever defining it. The patient nodded each time. Then she asked me afterwards what it meant. The honest answer is that nobody knows for sure yet, but here's what we're learning.
- ·4 min read·evidence
The plateau at month six: what to do, what not to do
Almost every patient on tirzepatide hits a stretch around month five or six where the scale stops moving for two or three weeks. The instinct is to push the dose higher. The instinct is usually wrong.
- ·5 min read·compound-guide
Switching from semaglutide to tirzepatide without losing the floor
The mistake most people make on the switch is treating it like upgrading a phone. The drugs work on different receptor mixes and the body needs a beat to recalibrate. Here's how to do it without the rebound.